These results are comparable to the reference NAM, PF-06372222, which had Glide XP docking and MM-GBSA binding energy scores of 6.68 and 58.9 6.1 kcal/mol, respectively
Health Canada Drug Product Database Ozempic, Wegovy, Rybelsus: Product listings, approved indications and current exclusivity status (Jan 4, 2026 expiry for semaglutide).
doi:10.1016/j.redox.2019.101107 217
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It would allow irritants in, moisture out and further cause inflammation