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Some research suggests these medications may cause mild vasodilation and potentially reduce systemic vascular resistance, which could trigger a compensatory increase in heart rate to maintain cardiac output and blood pressure

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Presented for research literature review only Khaksary Mahabady M et al

Mechanism: This effect is mediated by the activation of the vagus nerve and direct effects on gastric smooth muscle (Zheng et al., 2024)

A systematic review and meta-analysis of clinical trials