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The explanation for the discrepancy in the reduction of MACE in patients treated with SGLT2i in DECLARE-TIMI 58 suggests that the benefits of SGLT2i may be more pronounced in patients with a higher risk of cardiovascular disease

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Waist circumference reduction directly correlates with decreased visceral fat burden

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Further investigation of differential gene expression in -1 cells revealed that the most highly upregulated transcripts in response to liraglutide treatment were INS and IAPP (Figure 4, A and B, and Supplemental Figure 4A

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