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Inadequate mitochondrial Asp production is an important cause of T cell dysfunction, and lack of aspartate inhibits nicotinamide purine dinucleotide (NADH) production, causing ER expansion and TNF release
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Published 2025 Jun 10
Conversely, the pharmacological induction of GPx4 has been demonstrated to inhibit radiation-induced ferroptosis and to offer radioprotection in the murine model [67]
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