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While clinical translation of HAGSH scaffolds remains in its formative stage, HA-based hydrogels have already demonstrated favorable safety profiles and therapeutic efficacy in chronic ulcer management, providing a strong clinical precedent

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Preliminary data from our laboratories suggest that obesity and NAFLD may induce hyperglucagonemia via distinct mechanisms, potentially related to elevated amino acid and fatty acid levels that disrupt the liveralpha cell axis, as seen in NAFLD 86