Will determine the dual-indication labeling potential
OsDHAR was purified by Ni-NTA affinity chromatography [5 mL HisTrap FF column (GE Healthcare, Little Chalfont, UK) on an AKTA FPLC system] and eluted with a step gradient of 250 mM imidazole
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Both medications are administered as weekly injections and may cause similar side effects, including nausea or gastrointestinal discomfort
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Tirzepatide, the GLP-1 drug behind both Mounjaro and Zepbound, became the world's best-selling drug in the third quarter of 2025, surpassing Keytruda, a blockbuster immunotherapy drug from pharmaceutical giant Merck