why am i not losing weight on tirzepatide does work for me what to do if is working my not losing weight on semaglutide

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Molecular Identity Developer Eli Lilly Brand Names Mounjaro (diabetes), Zepbound (obesity) Mechanism Dual GLP-1 and GIP receptor agonist FDA Status Approved (2022 diabetes, 2023 obesity) Administration Weekly subcutaneous GIP Receptor Pathway The GIP receptor activation in Tirzepatide provides different metabolic effects than glucagon: Incretin enhancement: GIP augments GLP-1's insulin-related signaling Adipose tissue effects: GIP receptor expression in fat tissue documented Tolerability profile: Some research suggests GIP may moderate GI effects Synergistic incretin signaling: Two incretin pathways vs

Pregnancy and breastfeeding GLP-1 medications should be discontinued before attempting pregnancy

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594,595 It reprograms T cells, promoting proinflammatory Th17 phenotypes and aggressive CD8 + T-cell transformation