Thus, HGF, as a paracrine factor, may contribute to successful stem-cell-based therapies, which have been investigated in many clinical trials in the context of pathologies such as SCI, PD, ALS, AD, and MS with promising results ( Hepatocyte growth factor also acts on non-neural cells in the context of peripheral nerve regeneration, such as after a peripheral nerve injury
You may need to calm the system before pushing it harder
A broad synthesis is provided in the Thymosin 4 / TB-500 scoping review, Appl Sci 2026, which likewise stresses that translation to humans remains unproven
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