In a meta-analysis of 60 studies involving 60,077 T2D patients, GLP-1RAs marginally reduced the UACR in comparison to placebo and other antidiabetic agents, but resulted in no clinically relevant changes in eGFR (Kristensen et al., 2019)
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Circadian rhythm disruption causes a decrease in GLP-1 production.[ref] Blue light exposure at night from screens (phone, TV, tablet) or LED lightbulbs causes circadian rhythm disruption
Sleep Quality Enhancement: Anecdotal reports suggest that Ipamorelin supplementation may improve sleep quality and promote restful sleep patterns
Because Roseys skin changes appeared alongside reduced energy and coat thinning, her veterinarian performed a broader workup, which revealed hypothyroidism as a likely underlying contributor