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During the dose-escalation phase of STEP-1, weight loss at the 0.25 mg and 0.5 mg levels was minimal, generally in the range of 2 to 4%
Consistent with these biological effects, data from a large population-based cohort in Taiwan showed that initiation of GLP-1RAs, compared with insulin, was associated with a significantly lower incidence of HCC (HR = 0.47, 95% CI: 0.360.61) (Yang et al., 2024)
Healthcare providers have increasingly preferred Ozempic for its balanced efficacy and tolerability profile, further supported by favorable formulary placements and broad insurance coverage
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