The study examined safety parameters and metabolic biomarkers over a 12-week treatment period [2]
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[27] However, 3% to 6% of people given intravenous acetylcysteine show a severe, anaphylaxis-like allergic reaction, which may include extreme breathing difficulty (due to bronchospasm), a decrease in blood pressure, rash, angioedema, and sometimes also nausea and vomiting
For skin brightening, more frequent dosing (2-3x weekly) produces faster results
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Any research context involving competitive athletes must account for this