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But there is a trade-off: DAC also increases the potential for side effects (more on that below)
In practice, this degree of weight loss is difficult to achieve with lifestyle modifications, primarily dietary changes and regular moderate physical activity, though these are considered the cornerstone of weight management
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In TRIUMPH4 reporting, GI effects like nausea, diarrhoea, constipation, vomiting, and decreased appetite were also common
By increasing melanin production, users can develop a darker tan with less UV exposure than would normally be required
In the intestines, activation of FXR also regulates glucose and lipid metabolism [61] [62]
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