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The 15 mg/kg dose was selected based on established efficacy and safety relative to known copper toxicity thresholds
Bell LN
Similar results were obtained with mRNA expression of MMP-2 ( P =0.01), stromal-derived factor-1 (SDF-1) ( P =0.01), tumor growth factor (TGF)- ( P =0.001) and poly-(ADP-ribose) polymerase (PARP) that occurs in response to DNA damage ( P =0.001) (Figure 5b)
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Hepatology 72, 441453
GLP-1s seem to offer some benefit in brain health, says McIntyre
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