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By targeting both appetite and insulin signaling, tirzepatide often leads to more meaningful metabolic improvement and more sustainable weight loss over time

In the STEP and SUSTAIN clinical trial programmes, patients taking semaglutide at doses of 0.5mg to 1mg weekly achieved average weight reductions of 47% of their body weight over 6 to 12 months

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This process is exacerbated by smoking, pollution, exposure to UV or ionizing radiation, eating fried foods or those cooked at high temperatures, as well as engaging in high-intensity exercise (12)

Lanjewar D, Katariya R, Kale V et al (2025) Interplay of neuropeptide Y and autophagy in Alzheimers disease: therapeutic perspectives and mechanistic insights

As much as 64% of the some 50 million individuals with Alzheimers experience seizures, the scientists write