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Aging (Albany NY) (2021) 13(14):1901327

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Older adults (60+) May benefit from extended escalation intervals (6 weeks per step instead of 4) due to: Slower metabolic adaptation Increased medication sensitivity Higher likelihood of comorbid conditions Potential polypharmacy interactions Body Weight and Composition Factors Unlike some medications dosed per kilogram of body weight, cagrilintide uses fixed dosing regardless of baseline weight

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The potential benefits of semaglutide extend beyond weight loss, including improved metabolic markers and a reduced risk of obesity-related health issues