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In a prospective real-world cohort of 194 adults with type 2 diabetes initiating semaglutide or dulaglutide, only 49% achieved 5% weight loss by 12 months meaning that just under half of treated patients did not meet the threshold conventionally defined as clinically meaningful (Vozza et al., 2025)
-GLP-1 DPP-4, -GLP-1
Among the GLP-1 analogs, tirzepatide showed the most pronounced decrease in respiratory quotient (RQ) (Fig
Patients often report faster recovery, improved skin quality, reduced discomfort, and better gut function within weeks of starting treatment
Individuals with genetic variants in TNF or IL1B Saffron: Multiple clinical trials show that saffron may help with depression for some people
PMID: 54 SchiavonM.Dall'AcquaS.MiettoA.Pilon-SmitsE
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