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Applications: Osteoarthritis, sports injuries, and chronic joint pain

In most patients, desensitization offers slow, steady, and significant improvements within six to 12 months after initiation of treatment

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This paper established NNMT as a legitimate research target for adipose biology specifically and triggered the broader small-molecule NNMT inhibitor research that includes 5-Amino-1MQ

It is not a replacement for these medications but rather a different approach targeting a distinct metabolic pathway