Significant reductions in post-meal insulin concentrations and improved insulin sensitivity were also observed (Paradis 2011)
Ignatiadis, M., Sledge, G
Strategy FourA network that lives wherever patients do
How Wegovy works Wegovy mimics one hormone called GLP-1 (glucagon-like peptide-1), which has three main effects: Slows the movement of food through the stomach, helping people feel fuller for longer Acts on the brains appetite control centre (the hypothalamus) to reduce hunger Improves blood sugar control by enhancing insulin function The natural GLP-1 hormone lasts only minutes in the body before being cleared
GLP-1 agonists also reduce fasting insulin levels, improve glucose tolerance, and lower total testosterone by about 33%
So, on balance, the side effects of using these drugs are felt to be outweighed by the side benefits of losing weight