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Tirzepatide targets two gut hormones: GIP GLP-1 Both influence appetite, insulin release, and energy balance, and both act on brain circuits that: Regulate reward Motivation Satiety GLP-1 receptor activity reaches areas of the brain involved in mood and cognition, and experimental work suggests GLP-1 agonists can reduce brain inflammation and support neurons
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A small amount mixed with water before meals might ease symptoms
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Trulicity and Ozempic are popular GLP-1 receptor agonists FDA-approved to treat type 2 diabetes and lower the risk of serious cardiovascular problems in certain people with existing heart disease or risk factors for heart disease
