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As with all GLP-1 agonists, long-term post-marketing surveillance will be essential to characterize the pancreatic safety profile with greater statistical precision, particularly for rare events such as acute pancreatitis (estimated background rate of approximately 35 per 100,000 person-years in the general population) and the theoretical concern about pancreatic cancer
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You stare at the pen a little longer than necessary, reread the instructions for use twice, and wonder if you are about to pick the wrong injection site
In phase 3 studies, any site reaction was present in 0.6% of patients on the 0.5 mg dose, 0.3% on the 1 mg dose, and 0.8% in the comparator groups
An earlier meta-analysis of 45 studies found no relationship between the use of six different GLP-1 drugs and acne cases
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