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Exendin-4, the peptide isolated from Gila monster venomous saliva, became the foundation for exenatide, the first GLP-1 receptor agonist approved by the FDA in 2005 under the brand name Byetta
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NICE guideline NG28 supports the use of GLP-1 receptor agonists as add-on therapy to metformin when specific criteria are met, including inadequate glucose control despite optimised treatment
Do not use Ozempic if you are pregnant, breastfeeding, or about to become pregnant
Adam TC, Westerterp-Plantenga MS
Int J Obes 47(11):11321142 Thakur U et al (2021) Liraglutide augments weight loss after laparoscopic sleeve gastrectomy: a randomised, double-blind, placebo-control study
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