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An acceptable MS certificate for IGF-1 LR3 should show: Observed molecular weight matching theoretical mass within acceptable tolerance (~0.1%) No major masses corresponding to truncated sequences or non-native analogs Deconvolution data showing the correct multiply-charged ion series Together, HPLC + MS provides a two-dimensional confirmation: the correct compound (MS) at sufficient abundance (HPLC)

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The jury is still out, but there does seem to be some connectioneven drugmakers have acknowledged it

Despite negotiated price reductions announced in November that the White House said would make the drugs available at a dramatically lower cost to taxpayers and enable Medicaid to cover them, states are going ahead with the cuts, which providers say may undermine patients health

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