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Patients losing weight very rapidly face higher risk than those with more gradual weight reduction

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According to CNN, more than 70% of semaglutide prescriptions have gone to White patients White people are about four times more likely than Black people to have a prescription for a semaglutide medication, despite having nearly a 40% lower prevalence of diabetes and a 17% lower prevalence of obesity. So, White patients are receiving the vast majority of semaglutide prescriptions (Ozempic and Wegovy) by percentage, despite having a lower prevalence of both diabetes and obesity

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Integration of pharmacogenomics, metabolomics and microbiomics: Path to personalized metformin therapy Until recently, personalized medicine in T2D has predominantly focused on variation in DNA sequence

Based on GLP-1 receptor agonist class data, reducing the dose would be expected to produce less appetite suppression and a slower rate of weight loss or potential weight regain, as the pharmacological effect is dose-dependent