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6.10.4 Therapeutic strategies 6.10.4.1 Small molecules One study has proven that a potent ALK5 inhibitor, namely SB431542, can inhibit related molecules, such as TGF-, Smad3, Smad2, and a-SMA, and upregulates anti-fibrotic factor MMP2 in rats with DHEA-induced PCOS, thereby mitigating ovarian fibrosis via the TGF-/Smads signaling pathway (283)
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However, carnitine supplementation had no effects on lipid metabolism in African catfish 23 , hybrid tilapia 19 and hybrid striped bass 16
M., Jols, M., Mansuy, I
Levels of reduced and oxidized forms of GSH (GSSG) were also quantified in plasma, PBMCs, and RBCs isolated from T2DM subjects at pre- and post- L-GSH/or placebo supplementation
