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In our machine learning model, the progenitor population identified as progenitor-2 showed in general less age-related differences in DSB signal and dividing cell ratio compared to the progenitor-1 population

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Broad gene-mapping work led by Pickart and colleagues reported modulation of thousands of genes, with roughly a third of human gene patterns shifting toward expression states associated with younger or healthier tissue

That second pathway explains why prolonged deficiency causes neurological damage and not simply anaemia