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Lyophilization removes water under low temperature and vacuum, which helps preserve peptide stability during storage
However, a separate Phase 3 study in paediatric patients showed clinically meaningful overall survival, prompting AstraZeneca to proceed with regulatory submissions for the paediatric indication while continuing discussions with health authorities regarding the adult program
These cutting-edge studies suggest a broader scope of activity than previously documented, making the 10mg format ideal for longitudinal observation
Sources Food and Drug Administration
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BPC-157 activates endothelial nitric oxide synthase (eNOS), an enzyme responsible for producing NO in endothelial cells
