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GLP-1 medications, like semaglutide, work by regulating appetite and blood sugar, leading to steady, safe weight loss

This provides preclinical support for the recent phase III EVOKE/+ trial results and reinforces the notion that modulating metabolic or indirect anti-inflammatory pathways may be insufficient to counter amyloid-driven disease progression

We found that reduced UA and agricultural work, proxy for increased exposure to pesticides, were both associated with PD in the same cohort 13 , although the study was not designed to identify interaction effects

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