mtg mizzix commander deck of the Izmagnus For each card exiled this way Mizzix's Mastery | Commander 2015

Slash of Light is a two-mana monowhite instant spell that deals damage to a single creature equal to the number of creatures and equipment you have on your board

Accursed Duneyard Accursed Horde Acererak the Archlich Adorned Crocodile Adorned Pouncer Aim for the Head Angel of Sanctions Angrath, Captain of Chaos Anikthea, Hand of Erebos Anointer Priest Aphemia, the Cacophony Aphetto Vulture Archdemon of Unx Archghoul of Thraben Army of the Damned Ashnod, Flesh Mechanist Assemble from Parts Assemble the Rank and Vile Aven Eternal Aven Initiate Aven Wind Guide Awaken the Erstwhile Binding Mummy Bladewing, Deathless Tyrant Bleeding Edge Bone Miser Boneclad Necromancer Boneknitter Bridge from Below Call to the Grave Callous Dismissal Captive Audience Cellar Door Cemetery Reaper Cemetery Recruitment Champion of Wits Champion of the Perished Chill of the Grave Cleaver Skaab Clutch of Undeath Coat of Arms Commence the Endgame Compelling Deterrence Corpse Cobble Corpse Harvester Corpseweft Cradle of the Accursed Crawl from the Cellar Crowded Crypt Cruel Revival Crush Dissent Cryptbreaker Cryptcaller Chariot Curse of Disturbance Curse of Shallow Graves Curse of the Restless Dead Cursecloth Wrappings Dark Salvation Daryl, Hunter of Walkers Deadapult Deadly Plot Death Baron Death Tyrant Deathknell Berserker Deathmark Prelate Deluge of the Dead Diregraf Captain Diregraf Colossus Diregraf Horde Doomed Dissenter Drana's Chosen Draugr's Helm

Avacyn doesnt require you to go in an Angel kindred approach

It also has Ward, meaning it cannot be chosen or targeted by actions, abilities, or items, leaving your only option to get rid of it being a good old-fashioned challenge

Kaya the Inexorable Kaya the Inexorable protects one creature at a time, but few protection spells protect a creature from being exiled as well as destroyed

Channel lands, cycle lands, and fetchlands seem disgusting with this, not to mention the Field of the Dead-esque text